Biolegend Human CD28單抗(細(xì)胞治療級(jí)) 貨號(hào)302914
Biolegend Human CD28單抗(細(xì)胞治療級(jí)) 貨號(hào)302914
通用名稱(chēng):T淋巴細(xì)胞活化用抗人CD28單抗
Biolegend Human CD28單抗(細(xì)胞治療級(jí)) 貨號(hào)302914
CD28分子存在于大多數(shù)T細(xì)胞表面,被認(rèn)為是一種T細(xì)胞*的表面分子。T細(xì)胞對(duì)抗原的反應(yīng)性主要通過(guò)CD3/TCR復(fù)合物介導(dǎo),但也有賴(lài)于T細(xì)胞表面其他分子的協(xié)同。CD28與其天然配基B7結(jié)合可發(fā)揮共刺激作用,作為第二信號(hào)介紹T細(xì)胞激活,促進(jìn)T細(xì)胞增殖及分泌多種細(xì)胞因子并介紹導(dǎo)T,B細(xì)胞粘附。在體外T淋巴細(xì)胞激活擴(kuò)增中抗人CD28單克隆抗體通過(guò)第二信號(hào)通路發(fā)揮共刺激作用。
簡(jiǎn)單信息:
Clone: | CD28.2 (See other available formats) |
Isotype: | Mouse IgG1, κ |
Isotype Control: | LEAF™ Purified Mouse IgG1, κ Isotype Ctrl |
Workshop Number: | V-CD28.05 |
Reactivity: | Human, Cross-Reactivity: Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque, Squirrel Monkey, Capuchin Monkey, Sooty Mangabey |
Formulation: | 0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is <0.1 EU/µg of the protein (<0.01 ng/µg of the protein) as determined by the LAL test. |
Preparation: | The LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography. |
Concentration: | 1.0 mg/ml |
訂購(gòu)信息:
302913 規(guī)格:50ug
302914 規(guī)格:500ug
302923 規(guī)格:1mg